Clinical manifestations of PCOS and associated risks.
🔹 Menstrual dysfunction
<8 menstrual cycles per year
🔹Risk of endometrial cancer
“Since ovulation is rare or absent in PCOS, ovulation occurs (hyperplasia) of the endometrium, which can lead to bleeding” and also serves as a background for the development of endometrial cancer.
▫️ In women with PCOS, endometrial thickness> 7 mm may indicate hyperplasia☝🏻
🔹 Anovulatory infertility.
Women with PCOS ovulate infrequently, so it takes longer to conceive ⏳
🔹Hirsutism (male pattern excess body hair growth)
🔹Oesity and insulin resistance
📌 Obesity occurs in 50% of women with PCOS, in 30% – visceral obesity.
📌Most women with PCOS and https://pillintrip.com/de/medicine/postafen-meclozine are also insulin resistant, regardless of obesity, compared to women who do not.
📌Insulin resistance has been recognized as a major risk factor for type 2 diabetes.
📌 Factors such as obesity and a family history of type 2 diabetes can increase the risk of diabetes in PCOS.
With PCOS, the risks of developing atherosclerosis increase, and as a result of this, stroke, heart attack.
🔹 Complications during pregnancy 🤰
▫️ Women with PCOS have a higher risk of developing gestational complications such as miscarriage, gestational diabetes mellitus (GDM), hypertension, and preeclampsia ☝🏻
▫️These conditions put them at a higher risk of preterm birth and caesarean section.
🔹 Apnea in sleep.
Apnea (short-term respiratory arrest) during sleep – common in women with PCOS
▫️The main symptoms are loud snoring, fatigue and excessive daytime sleepiness.
▫️Mood disorders are, in principle, common among the population.
▫️ Women with PCOS may be more prone to mood disorders (depression and anxiety) compared to women without PCOS.
Women with PCOS are also at risk for eating disorders such as overeating and bulimia nervosa.